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Percocet is a combination of oxycodone and acetaminophen. Percocet is used when other pain medications don’t work well enough. It is a restricted substance due to the high risk for misuse, dependence, and addictive behavior.

Percocet (oxycodone/acetaminophen), how it works

Percocet is a combination medication that combines oxycodone and acetaminophen to treat pain.

  • Oxycodone is an opioid receptor-agonist. It attaches itself to mu-opioid sensory receptors within your brain to reduce the pain you experience.
  • Acetaminophen acts as an analgesic. It can reduce pain by stopping the production of certain chemicals.

Percocet is used to treat what?

  • Non-opioid medications are not enough to relieve pain.

What are the side effects of Percocet?

Serious side effects

If you notice any of these symptoms, contact your doctor immediately.

  • Dangerously Slow Breathing: Trouble breathing; blue-colored lips, toes, or fingers
  • Overdose (accidental overdose): slow breathing, extreme sleepiness or cold skin, upper-right stomach pain, dark urine or yellowing of the skin or eyes, cold or clammy hands, slowed heartbeat.
  • Withdrawal symptoms from opioids: Anxiety, restlessness, and suicidal thoughts. Runny noses, sweating, wide pupils, chills, yawning.
  • Severe allergic or skin reaction: rash or hives; blistering or peeling of the skin; shortness of breath, rapid heartbeat, feeling warm suddenly

As your body becomes accustomed to the medication, you may experience fewer side effects. If you experience any of these symptoms, or if they worsen, let your doctor know immediately.

Common side effects:

  • Dizziness
  • Sleepiness
  • Nausea
  • Vomiting
  • Constipation
  • Itching

Other Side Effects:

  • Headache
  • Sweating
  • Heartburn
  • Bloating
  • Changes in Taste
  • Stomach pain
  • Muscle pain
  • Blood pressure changes
  • Changes in heartbeat

Percocet (oxycodone/acetaminophen) dosage forms

  • 2.5mg/325mg
  • 5mg/325mg
  • 7.5mg/325mg
  • 10mg/325mg
  • 7.5mg/500mg
  • 10mg/650mg

Percocet dosage (oxycodone/acetaminophen)

Percocet is a combination of oxycodone and acetaminophen. Your doctor will prescribe the correct dose for you. To manage pain, it’s best to use the lowest possible dose for the shortest time.

There are different strengths of oxycodone in tablets and liquids. Be sure to know what Percocet product (oxycodone/acetaminophen) you are using and how you should take it. If you are unsure, ask your doctor.

  • In general, the typical starting dose for adults is 5 mg/325 mg (oxycodone/acetaminophen) by mouth every 6 hours as needed for pain.
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