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It is used when other pain medications don’t work well. It takes about thirty minutes for the pain to be relieved. This medication is restricted due to the high risk of abuse and dependence.

How does Norco (hydrocodone/acetaminophen) work?

Norco is a combination drug that combines two pain-relieving medications.

  • Hydrocodone acts as an opioid agonist. It attaches itself to mu-opioid receptors in the brain, reducing your pain.
  • Acetaminophen acts as an analgesic. It can reduce pain by stopping the production of certain chemicals.

What is Norco used for (hydrocodone/acetaminophen?

  • Non-opioid medications are not enough to relieve pain.

What are the side effects of Norco (hydrocodone/acetaminophen)?

Serious side effects

If you notice any of these symptoms, contact your doctor immediately.

  • Dangerously Slow Breathing: Trouble breathing; blue-colored lips, toes, or fingers
  • Overdose (accidental overdose): slow breathing, extreme sleepiness, and slow heartbeat. Upper right-sided stomach discomfort, dark urine, cold, clammy, or yellowed skin.
  • Withdrawal symptoms from opioids: Anxiety, restlessness, and suicidal thoughts. Runny nose, sweating, wide pupils, chills, sweating.
  • Severe allergic or skin reaction: rash or hives; blistering or peeling of the skin; shortness of breath, rapid heartbeat, dizziness, or feeling warm suddenly

As your body becomes accustomed to the medication, you may experience fewer side effects. If you experience any of these symptoms, or if they worsen, let your doctor know immediately.

Side effects of a common medication

  • Dizziness
  • Sleepiness
  • Nausea
  • Vomiting
  • Constipation
  • Itching

Other Side Effects

  • Headache
  • Tiredness
  • “Brain fog”
  • Stomach pain
  • Blood pressure changes

Norco (hydrocodone/acetaminophen) dosage forms





Typical dosing for Norco (hydrocodone/acetaminophen)

You and your provider will determine the best dose of Norco for you. It’s best to use the lowest possible dose for the shortest time to manage your pain.

There are different strengths of acetaminophen and hydrocodone in the liquids and tablets. Ask your provider if you are unsure which Norco product (hydrocodone/acetaminophen) you use and how to use it.

  • Generally, the typical starting dose for adults is 5 mg/325 mg (hydrocodone/acetaminophen) by mouth every 4 to 6 hours as needed for pain.
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